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KMID : 0358420110540120807
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 12 p.807 ~ p.811
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A case of unrecognized pregnancy during chemotherapy in non-small cell lung cancer patient
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Park Jee-Yoon
Park Jeong-Woo
Lee Dong-Ok
Park Chan-Wook
Park Joong-Shin
Jun Jong-Kwan
Syn Hee-Chul
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Abstract
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Most chemotherapeutic drugs are known to possess significant teratogenic effects. Although several agents have been proven to be safe for the fetus after organogenesis period, there is limited information on their use during pregnancy and it is very difficult to establish researches on the effect to human. We report a very unique case of unrecognized pregnancy in lung cancer patient who had been treated with variable agents of chemotherapy. A 25-year-old woman (gravida 0) who had been diagnosed as non-small cell lung cancer 6 years ago and received multiple regimens of chemotherapy presented at full term pregnancy with unknown gestational period. Without knowledge of pregnancy, she received a palliative chemotherapy with Docetaxel during first and second trimesters. Vaginal delivery with induction of labor due to postterm pregnancy was performed after evaluation of her medical condition and fetal surveillance. A 2,450 g female newborn was delivered with no evidence of congenital malformations.
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KEYWORD
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Pregnancy, Lung neoplasmas, Antineoplastic combined chemotherapy protocols
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